Heparinized Saline Flushed Catheter May Reduce Risk of Thrombosis in Cancer Patients Received Chemotherapy with Peripherally Inserted Central Catheter

Objective: This study investigated the effect of heparinized saline flushed catheter on preventing catheter-related thrombosis (CRT) among cancer patients received peripherally inserted central (PICC) for chemotherapy. Background: CRT is a common and serious complication when using PICC, which one most commonly used vascular access devices drug infusion, intravenous nutrition, Methods: prospective, paralled-group trial enrolled 300 chemotherapy who were randomly assigned to intervention (n=150) or control group. Besides basic procedure PICC combined with IC- ECG B-mode ultrasound imaging, catheters in group, while normal ones Hemorheology tests tip sites measurements outcome evaluation, incidences other complications. In additions, thromboelastogram (TEG) measure thrombus elastic before week after PICC. Results: 148 group 138 finished follow-ups, indicating longer duration more completion better positioning Intervention subjects showed significant lower complications (phlebitis, blockage, prolapse, local infection) (P <.05). additons, our proposed method may reduce incidence via significantly improving blood circulation Conclusion: Heparinized increase quality risk complications, circulation. Conclusions: can be easily introduced prolong placement improve